Thermo Fisher Scientific Phospho-RSK2 (Tyr529) Polyclonal Antibody
RSK2 단백질의 Tyr529 인산화 형태를 특이적으로 인식하는 폴리클로날 항체. Western blot에 적합하며, 인간과 생쥐 시료에서 반응. 1 mg/mL 농도의 액상 형태로, PBS 및 50% 글리세롤에 보관. 연구용으로만 사용 가능.
- 판매단위
- pk
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Applications
- Western Blot (WB): 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RPS6KA3 (Accession P51812), corresponding to amino acid residues around phosphorylated Tyr529. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2815863 |
Product Specific Information
This antibody detects endogenous levels of RSK2 only when phosphorylated at Tyr529.
Target Information
RPS6KA3 (RSK2) is a serine/threonine kinase that modulates various cellular processes including transcription, adhesion, growth, survival, and proliferation. It contains two non-identical kinase catalytic domains and phosphorylates substrates within the MAPK signaling pathway. The activity of RPS6KA3 is associated with cell growth and differentiation, and mutations in this gene have been linked to Coffin-Lowry syndrome (CLS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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