Thermo Fisher Scientific Pancreatic duodenal homeobox-1 protein (PDX1) Monoclonal Antibody (PCRP-PDX1-2C11)
인간 PDX1 단백질을 표적으로 하는 Mouse IgG2c 단일클론 항체로, 면역세포염색, 유세포분석, 펩타이드 어레이에 사용 가능. 고순도 Protein A/G 정제, 액상 형태로 제공되며 4°C 보관. 췌장 발달 및 인슐린 조절 연구에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2c |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PCRP-PDX1-2C11 |
| Immunogen | Recombinant full-length human PDX1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2.
The encoded nuclear protein is involved in early pancreatic development and plays a major role in glucose-dependent regulation of insulin gene expression.
Defects in this gene can cause pancreatic agenesis, leading to early-onset insulin-dependent diabetes mellitus (NIDDM) and maturity-onset diabetes of the young type 4 (MODY4).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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