Thermo Fisher Scientific H4K12ac Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Store vial at -20°C prior to opening.
• Aliquot contents and freeze at -20°C or below for extended storage.
• Avoid cycles of freezing and thawing.
• Centrifuge product if not completely clear after standing at room temperature.
• Stable for several weeks at 4°C as an undiluted liquid.
• Dilute only prior to immediate use.

A BLAST analysis suggests cross-reactivity with Alfalfa based on 100% sequence homology.
Cross-reactivity with Histone H4 [ac Lys12] from other sources has not been determined.

Target Information

Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fibers in eukaryotes. Two molecules of each core histone (H2A, H2B, H3, and H4) form an octamer around which approximately 146 bp of DNA is wrapped in repeating units called nucleosomes. The linker histone H1 interacts with linker DNA between nucleosomes and functions in chromatin compaction.
This gene is intronless, encodes a histone H4 family member, and is part of the large histone gene cluster on chromosome 6. Transcripts lack polyA tails but contain a palindromic termination element.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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