Thermo Fisher Scientific CDKN2C Monoclonal Antibody (OTI5G1), TrueMAB
CDKN2C 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI5G1). Western blot에 적합하며, 인간 시료에 반응. Affinity chromatography로 정제된 액상 항체로, PBS/BSA/glycerol buffer에 보관. 세포주기 조절 연구용.
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Applications
- Western Blot (WB): 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5G1 |
| Immunogen | Full length human recombinant protein of human CDKN2C produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene belongs to the INK4 family of cyclin-dependent kinase inhibitors. It interacts with CDK4 or CDK6 to prevent activation of CDK kinases, acting as a cell growth regulator controlling G1 phase progression. Overexpression suppresses cell growth in a manner dependent on wild-type RB1 function. Knockout mouse studies suggest roles in spermatogenesis regulation and tumorigenesis suppression. Two alternatively spliced transcript variants encoding the same protein have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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