Thermo Fisher Scientific KRAS Monoclonal Antibody (OTI4C6), TrueMAB
KRAS 단백질을 표적으로 하는 Mouse IgG1 단일클론 항체로, Western blot에 적합합니다. 인간 KRAS 전체 길이 재조합 단백질을 면역원으로 사용하였으며, 액상 형태로 제공됩니다. PBS/BSA/glycerol 버퍼에 저장되며 -20°C에서 보관합니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4C6 |
| Immunogen | Full length human recombinant protein of human KRAS produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
K-RAS (GTPase KRas) belongs to the Ras oncogene family. Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. It plays an important role in regulating cell proliferation and promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes in colorectal cancer cells in a ZNF304-dependent manner.
Mutations in the KRAS gene are associated with leukemia (acute myelogenous, juvenile myelomonocytic), Noonan Syndrome, gastric cancer, and cardiofaciocutaneous syndrome 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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