Thermo Fisher Scientific CDKN2C Monoclonal Antibody (OTI4G10), TrueMAB
CDKN2C 단백질을 인식하는 마우스 단클론 항체로, Western blot에 최적화되어 있습니다. Affinity chromatography로 정제되었으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 세포주기 조절 연구 및 CDK4/CDK6 관련 단백질 분석에 적합합니다.
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Applications and Tested Dilution
- Western Blot (WB): 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4G10 |
| Immunogen | Full length human recombinant protein of human CDKN2C produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. It interacts with CDK4 or CDK6 and prevents activation of these kinases, functioning as a cell growth regulator controlling G1 progression. Ectopic expression suppresses cell growth in correlation with wild-type RB1 function. Knockout mouse studies indicate roles in spermatogenesis regulation and tumorigenesis suppression. Two alternatively spliced transcript variants encoding an identical protein have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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