Thermo Fisher Scientific RGPD5 Polyclonal Antibody
인간 RGPD5 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 최적화되어 있습니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 내 0.02% sodium azide를 포함한 액상 형태입니다. RGPD5 연구 및 HIV 관련 연구에 활용 가능합니다.
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Applications
- Western Blot (WB): Tested dilution 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 23 amino acid peptide from near the center of human RGPD5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at –20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152288 |
Product Specific Information
- A suggested positive control is human thymus tissue lysate.
- PA5-20566 can be used with blocking peptide PEP-0686.
Target Information
The RANBP2-like and GRIP domain containing 5 protein (RGPD5) has high similarity to RANBP2, a large RAN-binding protein localized at the cytoplasmic side of the nuclear pore complex.
The gene coding for RGPD5 is thought to have arisen from a gene duplication event of RANBP2, as these highly homologous genes are located close to each other at chromosome 2q11–q12.
RGPD5 was identified as an HIV dependency factor (HDF), suggesting that RGPD5 may be an important drug target in HIV treatment.
At least two isoforms of RGPD5 are known to exist:
- The shorter isoform is expressed primarily in testis.
- The longer isoform is expressed at low levels in a number of somatic tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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