Thermo Fisher Scientific RGPD5 Polyclonal Antibody

Applications

• Western Blot (WB): Tested dilution 1 µg/mL

Product Specifications

Product Specific Information

• A suggested positive control is human thymus tissue lysate.
• PA5-20566 can be used with blocking peptide PEP-0686.

Target Information

The RANBP2-like and GRIP domain containing 5 protein (RGPD5) has high similarity to RANBP2, a large RAN-binding protein localized at the cytoplasmic side of the nuclear pore complex.
The gene coding for RGPD5 is thought to have arisen from a gene duplication event of RANBP2, as these highly homologous genes are located close to each other at chromosome 2q11–q12.
RGPD5 was identified as an HIV dependency factor (HDF), suggesting that RGPD5 may be an important drug target in HIV treatment.
At least two isoforms of RGPD5 are known to exist:

• The shorter isoform is expressed primarily in testis.
• The longer isoform is expressed at low levels in a number of somatic tissues.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.