Thermo Fisher Scientific ACOX1 Polyclonal Antibody
Rabbit polyclonal antibody against human ACOX1 for WB, IHC, and ICC applications. Affinity-purified with >95% purity by SDS-PAGE. Suitable for detecting fatty acid β-oxidation enzyme. For research use only.
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Thermo Fisher Scientific ACOX1 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein of human ACOX1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2720068 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
The ACOX1 protein is the first enzyme in the fatty acid β-oxidation pathway. It catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs and donates electrons directly to molecular oxygen, producing hydrogen peroxide. Defects in ACOX1 cause pseudoneonatal adrenoleukodystrophy, characterized by accumulation of very long-chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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