Thermo Fisher Scientific K-cadherin Polyclonal Antibody
K-cadherin 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot 및 IHC(Paraffin)에서 검증됨. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제되었으며, 고순도(>95%)를 보유. 연구용으로 세포 간 결합 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein of human K-cadherin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720070 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
Cadherins are a family of transmembrane glycoproteins involved in calcium-dependent cell–cell interactions. They play key roles in maintaining tissue integrity and morphogenesis.
Cadherins are categorized into type I and type II subgroups:
- Type I cadherins: E-cadherin (cadherin-1), N-cadherin (cadherin-2), P-cadherin (cadherin-3), and R-cadherin (cadherin-4)
- Type II cadherins: K-cadherin (cadherin-6) and OB-cadherin (cadherin-11)
K-cadherin (cadherin-6) is expressed in the proximal tubule epithelium of the kidney, from which most renal cell carcinomas originate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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