Thermo Fisher Scientific HLA-DP (MHC II) Recombinant Rabbit Monoclonal Antibody (HLA-DPB1/2862R)
HLA-DP(MHC II) 단백질을 인식하는 재조합 토끼 단일클론 항체. 인간 시료에 반응하며 ICC/IF, Flow Cytometry, ELISA에 적합. 고순도 Protein A/G 정제, 액상 형태로 4°C 보관. 면역펩티돔 연구 및 항원 제시 관련 연구에 유용.
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Thermo Fisher Scientific HLA-DP (MHC II) Recombinant Rabbit Monoclonal Antibody (HLA-DPB1/2862R)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
| ELISA | 2–4 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | HLA-DPB1/2862R |
| Immunogen | Non-T, non-B human acute lymphoblastic leukemia REH6 cell line |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The human MHC class II is encoded by three different isotypes: HLA-DR, -DQ, and -DP, all highly polymorphic. HLA-DP molecules are less studied but play a key role in immune recognition.
HLA-DP is a protein complex on antigen-presenting cells (dendritic cells, macrophages, B cells) that presents extracellular peptides to CD4+ T cells.
HLA and MHC antibodies are crucial in immunopeptidomics, aiding identification and characterization of neoantigens via high-performance liquid chromatography coupled with tandem mass spectrometry.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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