Thermo Fisher Scientific CENPA Monoclonal Antibody (3-19)
CENPA 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot, IHC, ICC/IF 등 다양한 응용에 사용 가능. 인간 및 닭 시료 반응성. Protein A로 정제된 액상 형태이며, 장기 보관 시 -20°C에서 보관 권장.
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Thermo Fisher Scientific CENPA Monoclonal Antibody (3-19)
Applications 및 Tested Dilution
| 응용 분야 | 희석 배수 | 관련 문헌 |
|---|---|---|
| Western Blot (WB) | 1 µg/mL | View 1 publication |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL | - |
| Immunocytochemistry (ICC/IF) | 10 µg/mL | View 2 publications |
| Immunoprecipitation (IP) | - | View 1 publication |
| Neutralization (Neu) | Assay-dependent | - |
| CUT&RUN (C&R) | - | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Chicken, Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3-19 |
| Immunogen | Synthetic peptide corresponding to residues P(3) R R R S R K P E A P R R R S P S(19) of human CENPA protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2078763 |
Product Specific Information
- Recommended positive controls: BE cells
- Does not cross-react with mouse CENPA proteins
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Centromeres are differentiated chromosomal domains that specify the mitotic behavior of chromosomes.
CENPA encodes a centromere protein containing a histone H3-related histone fold domain required for targeting to the centromere.
CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure, replacing one or both copies of conventional histone H3 in the (H3-H4)₂ tetrameric core of the nucleosome particle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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