Thermo Fisher Scientific pro-Brain Natriuretic Peptide Monoclonal Antibody (13G12)
인간 proBNP를 특이적으로 인식하는 단클론 항체로 심장 관련 연구용에 적합. Western blot 및 ELISA 등 다양한 분석에 사용 가능. 높은 순도의 Protein A 정제 항체로 안정적 성능 제공. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 13G12 |
| Immunogen | Synthetic peptide corresponding to the N-terminal residues E(13) T S G L Q E Q R N H L Q G K(27) of human proBNP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 5.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2251639 |
Product Specific Information
MA1-20886 detects proBNP in human samples.
Target Information
In cardiac tissue, brain natriuretic peptide (BNP) is synthesized as a 134 amino acid precursor (prepro-BNP), which is cleaved by proteases to form a 26 aa signal peptide and a 108 aa pro-BNP. Proteolytic digestion of pro-BNP results in formation of a 76 aa amino-terminal NT-proBNP and a biologically active 32 aa BNP hormone molecule. Both proBNP and NT-proBNP circulate in human plasma and have been proposed as markers for early diagnosis of left ventricular dysfunction as well as prognostic markers for possible cardiac complications in patients with heart failure.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: MA1-20886_pro-Brain_Natriuretic_Peptide_P16860-1_House_mouse.svg)
(이미지 파일명: MA1-20886_pro-Brain_Natriuretic_Peptide_P16860-1_House_mouse_PDP.jpeg)
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