Thermo Fisher Scientific GRB10 Polyclonal Antibody
GRB10 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunoprecipitation에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 인체 유래 GRB10 단백질(1-50 aa)에 대한 특이성을 가집니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 and 50 of human growth factor receptor-bound protein 10 (GRB10) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
GRB7 is a SH2 domain protein with a single SH2 domain at its C-terminal, a central region similar to Ras GAP, and a proline-rich N terminus. A related SH2 domain-containing protein, GRB10, shows high homology with GRB7. GRB10 undergoes serine (but not tyrosine) phosphorylation in response to EGF treatment and binds poorly to the EGF receptor. GRB10 maps to mouse chromosome 11, near the EGF receptor, while GRB7 maps to the same chromosome close to HER2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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