Thermo Fisher Scientific MAGP-2 Polyclonal Antibody

Thermo Fisher Scientific MAGP-2 Polyclonal Antibody

Applications and Tested Dilution

• Western Blot (WB): 1:250–1:1,000
• ELISA: 1:5,000–1:20,000

Product Specifications

Product Specific Information

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use.

This affinity-purified antibody is directed against human MAGP-2 protein. BLAST analysis suggests cross-reactivity with MAGP-2 protein from human and chimpanzee based on 100% homology with the immunizing sequence. Partial reactivity is expected with MAGP-2 from mouse, dog, and rat sources (~75% sequence homology). Reactivity against homologues from other species is not known.

Target Information

This gene encodes a 25-kDa microfibril-associated glycoprotein rich in serine and threonine residues. It lacks a hydrophobic carboxyl terminus and proline-, glutamine-, and tyrosine-rich regions, which are characteristics of the related 31-kDa microfibril-associated glycoprotein (MFAP2). The similarity between these two proteins is confined to a central region of 60 amino acids, where alignment of seven cysteine residues occurs. Structural differences suggest distinct functions from MFAP2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.