Thermo Fisher Scientific YBX1 Polyclonal Antibody
Thermo Fisher Scientific의 YBX1 Polyclonal Antibody는 Human YBX1 단백질을 인식하는 Rabbit IgG 항체로, WB 및 ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 비특이적 밴드 정보와 저장 조건이 명확히 제공됩니다. 연구용으로만 사용됩니다.
- 카탈로그번호
- PA519453
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1–1.4 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide conjugated to KLH derived from within residues 1–100 of Human YB1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10988345 |
Product Specific Information
- For Western Blot, this antibody has non-specific bands at 50 kDa.
- This antibody is predicted to react with Xenopus laevis based on sequence homology.
- Store antibody at 4ºC for 1–2 weeks. For long-term storage, store at -20ºC.
Target Information
YBX1 binds to splice sites in pre-mRNA and regulates splice site selection.
It stabilizes cytoplasmic mRNA and modulates translation by interacting with eukaryotic initiation factors.
YBX1 binds to promoters containing a Y-box (5'-CTGATTGGCCAA-3'), such as HLA class II genes, and regulates transcription.
It promotes separation of mismatched or cisplatin-modified DNA strands, exhibits endonucleolytic activity, and may play a role in DNA repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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