Thermo Fisher Scientific c-Myc Monoclonal Antibody (2G8D5), HRP, THE
HRP 결합된 c-Myc 단일클론 항체로 융합 단백질 내 c-Myc 발현 검출에 적합. WB, ICC/IF, ELISA, IP 등 다양한 응용 가능. 단백질 A 정제, 동결건조 형태로 안정적 보관 가능. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunocytochemistry (ICC/IF) | 1 µg/mL |
| ELISA | 0.05–0.2 µg/mL |
| Immunoprecipitation (IP) | 1 µg/mL |
| Miscellaneous PubMed (Misc) | – |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Tag |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2G8D5 |
| Immunogen | Synthetic peptide corresponding to residues 410–419 (EQKLISEEDL) coupled to KLH |
| Conjugate | HRP |
| Form | Lyophilized |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.01% thimerosal |
| Storage Conditions | −20°C or −80°C if preferred |
| Shipping Conditions | Wet ice |
Additional formats available:
Product Specific Information
Reconstitute the lyophilized antibody with deionized water (or equivalent) to a final concentration of 0.5 mg/mL.
GenScript THE™ c-Myc Antibody [HRP], mAb, Mouse is immunoaffinity purified from mouse ascites with protein A and conjugated to horseradish peroxidase.
This monoclonal antibody is suitable for detecting the expression level of c-Myc in fusion proteins.
Target Information
Myc is a proto-oncogene encoding a nuclear phosphoprotein that regulates cell cycle progression, apoptosis, and cellular transformation.
It forms a heterodimer with transcription factor MAX, binding to the E-box DNA consensus sequence to regulate transcription of target genes.
Amplification of this gene is frequently observed in various human cancers.
Translocations involving Myc are associated with Burkitt lymphoma and multiple myeloma.
Translation initiates from both an upstream non-AUG (CUG) and a downstream AUG start site, producing two isoforms with distinct N-termini.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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