Thermo Fisher Scientific PTH1, Parathyroid Hormone Receptor 1 Polyclonal Antibody
PTH1 수용체를 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태입니다. 인체 시료 반응성이 검증되었으며, 연구용으로 사용됩니다.
- 카탈로그번호
- 7TM0331N-IC
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PTH1, Parathyroid Hormone Receptor 1 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 1 publication |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 | – |
| Immunocytochemistry (ICC/IF) | 1:200 | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide with sequence EEASGPERPPALLQEEWETVM corresponds to amino acids 473–493 of human PTH1. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
Parathyroid hormone receptor 1 (PTH1R) is a member of the G-protein coupled receptor family. It acts as a receptor for parathyroid hormone (PTH) and parathyroid hormone-like hormone (PTHLH). The receptor mediates its activity via G proteins, activating adenylyl cyclase and the phosphatidylinositol-calcium second messenger system.
Mutations in this receptor are associated with Jansen’s metaphyseal chondrodysplasia (JMC), Blomstrand chondrodysplasia (BOCD), and enchondromatosis.
Expression of PTH1R has been reported in bone, breast, brain, colon, gastrointestinal tract, kidney, liver, placenta, skin, umbilical cord, and uterus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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