Thermo Fisher Scientific PTH1 (Parathyroid Hormone Receptor 1) Polyclonal Antibody
PTH1(Parathyroid Hormone Receptor 1)에 특이적인 Rabbit Polyclonal Antibody로, WB, IHC, ICC 등 다양한 응용에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, Human 시료 반응성. 단기 4°C, 장기 -20°C 보관 권장.
- 카탈로그번호
- 7TM0331N
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 1 publication |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 | - |
| Immunocytochemistry (ICC/IF) | 1:200 | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide with sequence EEASGPERPPALLQEEWETVM corresponding to amino acids 473–493 of human PTH. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
Parathyroid hormone receptor 1 (PTH1R) is a member of the G-protein coupled receptor family. It acts as a receptor for parathyroid hormone (PTH) and parathyroid hormone-like hormone (PTHLH). The receptor’s activity is mediated by G proteins that activate adenylyl cyclase and a phosphatidylinositol-calcium second messenger system.
Defects in this receptor are associated with Jansen’s metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), and enchondromatosis.
PTH1R expression has been reported in bone, breast, brain, colon, GI, kidney, liver, placenta, skin, umbilical cord, and uterus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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