Thermo Fisher Scientific MRPL28 Polyclonal Antibody
Thermo Fisher Scientific의 MRPL28 폴리클로날 항체는 인간 MRPL28 단백질을 인식하며, Western blot과 IHC(P)에서 검증되었습니다. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 50–256 of Human MRPL28 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.7 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547865 |
Product Specific Information
- Recommended positive controls: A549, HeLa, HepG2
- Predicted reactivity: Mouse (89%), Bovine (89%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
MRP-L28 (39S ribosomal protein L28, melanoma-associated antigen recognized by T lymphocytes) is a mitochondrial protein belonging to the ribosomal protein L28P family.
MRP-L28 may serve as a therapeutic reagent for HLA-A24 (A24) patients, as it is recognized by tumor-infiltrating lymphocyte (TIL) 1290 targeting the A24 serotype.
HLA-A24 is a serotype identifying common HLA-A24 gene products and is prevalent in Austronesia, Papua New Guineans, indigenous Taiwanese, Yupik, and Greenland Eskimos.
MRP-L28 is expressed in various normal tissues including spleen, testis, thymus, liver, kidney, brain, adrenal, lung, and retinal tissue.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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