Thermo Fisher Scientific BAIAP2 Polyclonal Antibody
BAIAP2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, WB, IHC, ICC, IP 등 다양한 응용에 적합합니다. 인간, 생쥐, 랫드에 반응하며 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:20,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | - |
| Immunoprecipitation (IP) | Assay-dependent | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–219 of Human BAIAP2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.7 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547860 |
Product Specific Information
- Recommended positive controls: SK-N-SH, mouse brain, rat brain
- Predicted reactivity: Mouse (98%), Rat (98%), Bovine (98%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene is a brain-specific angiogenesis inhibitor (BAI1)-binding protein. It acts as an adaptor linking membrane-bound G-proteins to cytoplasmic effector proteins and functions as an insulin receptor tyrosine kinase substrate, suggesting a role for insulin in the central nervous system. It associates with Rho small G protein effectors involved in stress fiber formation and cytokinesis, contributing to lamellipodia and filopodia formation in motile cells and neuronal growth-cone guidance. It also interacts with the dentatorubral-pallidoluysian atrophy gene associated with a neurodegenerative disease. Alternative splicing produces multiple transcript variants encoding distinct isoforms.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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