Thermo Fisher Scientific H3K4me3 Recombinant Rabbit Monoclonal Antibody (RM340), ChIP-Verified
Histone H3K4me3에 특이적으로 반응하는 재조합 토끼 단클론 항체로, ChIP 검증 완료. ELISA, ChIP, ChIP-Seq, Luminex 등 다양한 응용에 적합. 인간 시료 반응성, 고순도 Protein A 정제, 안정적 액상 형태로 제공.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| ELISA | 1–10 µg/mL |
| ChIP assay | 1–5 µg/mL |
| ChIP-sequencing | 3 µg |
| Luminex | 0.5–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | RM340 |
| Immunogen | A trimethyl-peptide corresponding to Trimethyl-Histone H3 (Lys4) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 50% glycerol, 1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C |
| RRID | AB_2866509 |
Product Specific Information
This antibody specifically reacts with Histone H3 trimethylated at Lysine 4 (H3K4me3).
No cross-reactivity with monomethylated (K4me1), dimethylated (K4me2), or other methylations in histone H3.
Click here for Master Lot linking information
Target Information
Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells.
It, along with four core histone proteins, binds to DNA to form the nucleosome structure.
Histones play a central role in transcription regulation, DNA repair, DNA replication, and chromosomal stability.
Post-translational modifications of histones can alter chromatin structure or facilitate transcription factor binding.
The N-terminal tail of histone H3 undergoes methylation, acetylation, and phosphorylation, influencing cellular processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: MA5-33382-20UG_H3K4me3_P68431-1_Rabbit.svg, MA5-33382-20UG_H3K4me3_Q71DI3-1_Rabbit.svg 등)
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