Thermo Fisher Scientific SERPINB6 Monoclonal Antibody (OTI1C5), TrueMAB

Applications and Tested Dilutions

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, it is recommended to perform desalting (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

The SERPINB6 gene encodes a member of the serpin superfamily and the ovalbumin-serpin subfamily. Initially identified as a placental thrombin inhibitor, its mouse homolog is expressed in the hair cells of the inner ear.
Mutations in this gene are linked to nonsyndromic progressive hearing loss, indicating its role in protecting inner ear cells from lysosomal leakage during stress. Loss of this function can lead to cell death and sensorineural hearing loss.
Alternative splicing variants have been identified for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.