Thermo Fisher Scientific USP10 Monoclonal Antibody (OTI1A10), TrueMAB
USP10 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI1A10). Western blot, IHC, Flow cytometry에 적합. HEK293T 세포에서 발현된 full-length human USP10 항원을 면역원으로 사용. 동결건조 형태, PBS buffer에 8% trehalose 포함, 보존제 없음.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A10 |
| Immunogen | Full length human recombinant USP10 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
When using this carrier-free antibody for conjugation experiments, an additional desalting step is recommended (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
USP10 (Ubiquitin Specific Peptidase 10) is a cysteine protease belonging to the ubiquitin-specific protease family.
It catalyzes the cleavage of ubiquitin from conjugated substrates such as p53/TP53, SNX3, and CFTR.
USP10 is also identified as a subunit of DNA-bound androgen receptor (AR) complexes and may regulate AR activity.
Furthermore, USP10 acts as a key regulator of p53 stability and is considered a potential tumor suppressor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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