Thermo Fisher Scientific Phospho-SMAD3 (Ser423, Ser425) Recombinant Rabbit Monoclonal Antibody (ST0493)
Phospho-SMAD3 (Ser423, Ser425) 특이적 재조합 토끼 모노클로날 항체로, WB, IHC, ICC/IF에 사용 가능. Human 및 Mouse 반응성. Protein A 정제, 1 mg/mL 농도, 장기 보관 시 -20°C 권장. 연구용 전용 제품.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2000–1:5000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ST0493 |
| Immunogen | Synthetic phospho-peptide corresponding to residues surrounding Ser423 and Ser425 of human Smad3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 0.05% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2898924 |
Target Information
SMAD3 belongs to the SMAD family of proteins, similar to the gene products of the Drosophila gene mothers against decapentaplegic (Mad) and the C. elegans gene Sma.
SMAD proteins are signal transducers and transcriptional modulators mediating multiple signaling pathways.
This protein functions as a transcriptional modulator activated by transforming growth factor-beta (TGF-β) and is thought to play a role in the regulation of carcinogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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