Thermo Fisher Scientific SHP2 Recombinant Rabbit Monoclonal Antibody (SN72-02)
SHP2 단백질을 표적으로 하는 토끼 단클론 항체로, Western blot, IHC, IP 등 다양한 응용에 적합합니다. HEK293 세포에서 발현된 재조합 항체이며, Protein A로 정제되었습니다. 인간, 마우스, 랫트에 반응하며 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SN72-02 |
| Immunogen | Synthetic peptide within N-terminal human SHP2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2898923 |
Target Information
The protein encoded by this gene belongs to the protein tyrosine phosphatase (PTP) family, which regulates various cellular processes such as cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 (SH2) domains that function as phospho-tyrosine binding domains and mediate substrate interactions. It is widely expressed and plays a regulatory role in signaling events critical for mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are associated with Noonan syndrome and acute myeloid leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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