Thermo Fisher Scientific Dab1 Polyclonal Antibody
마우스 Dab1 단백질에 특이적인 폴리클로날 항체로, WB, IHC, ELISA, IP에 사용 가능. 75 mg/mL 액상 형태로 제공되며, -20°C 보관 권장. 뇌 발달 연구 및 신호전달 경로 분석에 적합.
- 카탈로그번호
- 100-401-225x (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Dab1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:5,000 |
| Immunohistochemistry (IHC) | 1:5,000 |
| ELISA | 1:10,000–1:50,000 |
| Immunoprecipitation (IP) | 1 µL/500 µg |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | This whole rabbit serum was prepared by repeated immunizations with a synthetic peptide corresponding to the C-terminal region of murine Dab1 at amino acids 400–555. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 75 mg/mL |
| Storage Buffer | 0.02M potassium phosphate/whole serum, pH 7.2, with 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing.
Centrifuge product if not completely clear after standing at room temperature.
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use.
This antibody is directed against Dab1 from mouse. Cross-reactivity with other species has not been determined. No reaction occurs with human or mouse Dab2.
Target Information
The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene (Dab1) plays a central role in brain development, directing the migration of cortical neurons to their proper layer.
The Dab1 protein acts as a signal transducer interacting with protein kinase pathways to regulate neuronal positioning in the developing brain.
Alternatively spliced transcript variants have been reported, but their full-length nature has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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