Thermo Fisher Scientific Dab1 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing.
Centrifuge product if not completely clear after standing at room temperature.
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use.

This antibody is directed against Dab1 from mouse. Cross-reactivity with other species has not been determined. No reaction occurs with human or mouse Dab2.

Target Information

The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene (Dab1) plays a central role in brain development, directing the migration of cortical neurons to their proper layer.
The Dab1 protein acts as a signal transducer interacting with protein kinase pathways to regulate neuronal positioning in the developing brain.
Alternatively spliced transcript variants have been reported, but their full-length nature has not been determined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.