Thermo Fisher Scientific COL1A2 Polyclonal Antibody
COL1A2 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF에 적합합니다. 인간 및 생쥐 시료에 반응하며, 액상 형태로 제공됩니다. Affinity chromatography로 정제되었으며, PBS/glycerol buffer에 보관됩니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific COL1A2 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human COL1A2 (Accession P08123), corresponding to amino acid residues M1–P34 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2854224 |
Product Specific Information
This antibody detects endogenous levels of total Collagen I alpha 2.
Target Information
The COL1A2 gene encodes the pro-alpha2 chain of type I collagen, which forms a triple helix with two alpha1 chains and one alpha2 chain. Type I collagen is a fibril-forming collagen present in most connective tissues and abundant in bone, cornea, dermis, and tendon.
Mutations in this gene are linked to osteogenesis imperfecta types I–IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome.
Symptoms from COL1A2 mutations are generally less severe than those from COL1A1 mutations, reflecting distinct roles in matrix integrity. Three transcripts have been identified due to alternative polyadenylation signals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.