Thermo Fisher Scientific GPX4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:15,000-1:60,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 74-197 of GPX4 (NP_002076.2). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GPX4,uniProtId:P36969-1,ncbiNodeId:9606,antigenRange:74-197,antigenLength:197,antigenImageFileName:PA5-120674_GPX4_P36969-1_Rabbit.svg,antigenImageFileNamePDP:PA5-120674_GPX4_P36969-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.74 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.09% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2914246

Product Specific Information

Positive test controls include: U-87MG, Mouse testis, Mouse kidney, Rat testis. The target is usually found in the following locations: Cytoplasm, Mitochondrion.

Immunogen sequence: GKTEVNYTQL VDLHARYAEC GLRILAFPCN QFGKQEPGSN EEIKEFAAGY NVKFDMFSKI CVNGDDAHPL WKWMKIQPKG KGILGNAIKW NFTKFLIDKN GCVVKRYGPM EEPLVIEKDL PHYF

Target Information

Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.