Thermo Fisher Scientific S100A10 Polyclonal Antibody
S100A10 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합. Human, Mouse, Rat 등 반응성 보유. 고순도 Affinity Chromatography 정제, 안정적인 PBS/glycerol 저장 조건 제공.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 1–97 of human S100A10 (NP_002957.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.32 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914251 |
Product Specific Information
- Positive test controls include: Rat lung
- Immunogen sequence:
MPSQMEHAME TMMFTFHKFA GDKGYLTKED LRVLMEKEFP GFLENQKDPL AVDKIMKDLD QCRDGKVGFQ SFFSLIAGLT IACNDYFVVH MKQKGKK
Target Information
The S-100 family of calcium-activated proteins interacts with various target proteins to modulate biological signaling pathways. Many cancer cell lines overexpress the plasminogen receptor S-100A10 on the extracellular surface, forming a heterotetrameric complex with Annexin II. This association is not required for plasma membrane localization or plasminogen activation. Additionally, S-100A10 acts as a chaperone for hepatitis B virus polymerase, facilitating its nuclear translocation and suggesting a role in viral replication regulated by intracellular calcium.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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