
Thermo Fisher Scientific PSMD2 Polyclonal Antibody
Thermo Fisher Scientific PSMD2 Polyclonal Antibody는 인간 및 마우스 시료에서 PSMD2 단백질 검출에 적합한 다클론 항체입니다. Western blot, ICC/IF, ELISA에 사용 가능하며, 고순도 액상 형태로 제공됩니다. -20°C 보관이 권장됩니다.
- 카탈로그번호
- PA5120681
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:200
ELISA
- Tested Concentration: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–260 of human PSMD2 (NP_002799.3) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.79 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914253 |
Product Specific Information
- Positive test controls include: SW480, OVCAR3, M21, U-937, SH-SY5Y, Mouse testis, Mouse heart, Mouse liver.
Immunogen sequence:
MEEGGRDKAP VQPQQSPAAA PGGTDEKPSG KERRDAGDKD KEQELSEEDK QLQDELEMLV ERLGEKDTSL YRPALEELRR QIRSSTTSMT SVPKPLKFLR PHYGKLKEIY ENMAPGENKR FAADIISVLA MTMSGERECL KYRLVGSQEE LASWGHEYVR HLAGEVAKEW QELDDAEKVQ REPLLTLVKE IVPYNMAHNA EHEACDLLME IEQVDMLEKD IDENAYAKVC LYLTSCVNYV PEPENSALLR CALGVFRKFS
Target Information
The 26S proteasome is a multicatalytic proteinase complex composed of a 20S core and a 19S regulator. The 20S core consists of four rings of 28 non-identical subunits (two alpha and two beta rings), while the 19S regulator includes a base (six ATPase and two non-ATPase subunits) and a lid (up to ten non-ATPase subunits). Proteasomes are abundant in eukaryotic cells and cleave peptides in an ATP/ubiquitin-dependent, non-lysosomal pathway. The immunoproteasome plays a key role in MHC class I peptide processing. PSMD2 encodes one of the non-ATPase subunits of the 19S regulator lid and may also be involved in TNF signaling via interaction with the TNF receptor. A pseudogene exists on chromosome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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