Thermo Fisher Scientific MB67 Polyclonal Antibody
Thermo Fisher Scientific의 MB67 Polyclonal Antibody는 Human, Mouse, Rat에 반응하는 Rabbit IgG 항체로, Western blot, ICC/IF, ELISA, IP에 사용됩니다. Affinity 정제된 액상 형태로, PBS/glycerol buffer에 보관되며 연구용으로 적합합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
| Immunoprecipitation (IP) | 0.5–4 µg antibody for 200–400 µg extracts |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 103–352 of human NR1I3 (NP_001070948.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.9 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914250 |
Product Specific Information
- Positive test controls: HT-29, Mouse liver, Rat liver
- Subcellular localization: Cytoplasm, Nucleus, Cytoskeleton
Immunogen sequence:
PVQLSKEQEE LIRTLLGAHT RHMGTMFEQF VQFRPPAHLF IHHQPLPTLA PVLPLVTHFA DINTFMVLQV IKFTKDLPVF RSLPIEDQIS LLKGAAVEIC HIVLNTTFCL QTQNFLCGPL RYTIEDGARV SPTVGFQVEF LELLFHFHGT LRKLQLQEPE YVLLAAMALF SPDRPGVTQR DEIDQLQEEM ALTLQSYIKG QQRRPRDRFL YAKLLGLLAE LRSINEAYGY QIQHIQGLSA MMPLLQEICS
Target Information
This gene encodes a member of the nuclear receptor superfamily and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or as a heterodimer with the retinoid X receptor, regulating transcription of genes involved in drug metabolism and bilirubin clearance (e.g., cytochrome P450 family). Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is modulated by both agonists and inverse agonists.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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