Thermo Fisher Scientific Human beta-NGF Recombinant Protein
인간 유래 beta-NGF 재조합 단백질로 신경세포 생존 및 분화 연구에 적합함. E. coli 발현 시스템 사용, ≥98% 고순도. 기능적 활성 검증 완료. 장기 보관 시 -20°C 이하에서 안정적이며 반복 동결·해동은 피해야 함.
- 카탈로그번호
- PHG0126
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Human beta-NGF Recombinant Protein
Applications
- Western Blot (WB): Assay-dependent
- Immunohistochemistry (IHC): Assay-dependent
- ELISA: Assay-dependent
- Functional Assay: Assay-dependent
- Control (Ctrl): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Expression System | E. coli |
| Amino Acid Sequence | SSSHPIFHRG EFSVCDSVSV WVGDKTTATD IKGKEVMVLG EVNINNSVFK QYFFETKCRD PNPVDSGCRG IDSKHWNSYC TTTHTFVKAL TMDGKQAAWR FIRIDTACVC VLSRKAVRRA |
| Molecular Weight | 27 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | ≥98% by SDS-PAGE and HPLC |
| Endotoxin Concentration | <0.1 ng/µg |
| Activity | ED50 ≤ 1.0 ng/mL; determined by the dose-dependent proliferation of human TF-1 cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Purified |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Wet or Dry ice (international) |
Product Specific Information
Carrier-Free
- Lyophilized protein is stable at room temperature for 1 month.
- For long-term storage, keep at -20°C.
- Working aliquots stored with a carrier protein are stable for at least 12 months at -20°C to -80°C.
- Avoid repeated freeze/thaw cycles.
Target Information
Nerve growth factor (NGF) influences the survival and differentiation of various neuronal and nonneuronal cells. NGF binds to specific cell surface receptors with high and low affinity; only the high-affinity receptor mediates signal transduction. Cross-linking studies with 125I-NGF show that the high-affinity receptor of rat PC12 cells forms a 158,000 Mr complex with NGF, while the low-affinity receptor forms a 100,000 Mr complex.
Full-length cDNA clones for human and rat NGF receptor genes show over 90% homology. NGF exhibits nerve growth-stimulating activity and regulates growth and differentiation of sympathetic and sensory neurons. Mutations in the NGF gene are linked to hereditary sensory and autonomic neuropathy type 5 (HSAN5), and dysregulation of NGF expression is associated with allergic rhinitis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.