Thermo Fisher Scientific CHRNA4 Recombinant Rabbit Monoclonal Antibody (23GB5085)
CHRNA4 단백질을 인식하는 토끼 단클론 항체로 Western blot과 유세포분석에 적합. HEK293F 발현 시스템에서 제조된 재조합 항체이며, 친화 크로마토그래피로 정제됨. 인간 시료에 반응하며, PBS/glycerol 용액 형태로 제공됨.
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Applications and Tested Dilution
- Western Blot (WB): 1:1,000–1:5,000
- Flow Cytometry (Flow): 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB5085 |
| Immunogen | A synthesized peptide derived from human ACHA4 (540–600 AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
The CHRNA4 gene encodes a nicotinic acetylcholine receptor subunit, part of a ligand-gated ion channel superfamily involved in fast synaptic transmission. These pentameric receptors bind acetylcholine, triggering conformational changes that open ion channels across the plasma membrane. The CHRNA4 protein interacts with nAChR beta-2 or beta-4 subunits to form functional receptors. Mutations in this gene are associated with nocturnal frontal lobe epilepsy type 1, and certain polymorphisms may confer protection against nicotine addiction.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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