Thermo Fisher Scientific IL-27 p28 Recombinant Superclonal Antibody (7HCLC)

Applications

• Western Blot (WB): 1–3 µg/mL

Product Specifications

Product Specific Information

Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They combine multiple recombinant monoclonal antibodies, providing the sensitivity of polyclonal antibodies with the specificity and consistency of monoclonal antibodies.
These antibodies recognize multiple epitopes on the target, offering high detection sensitivity for low-abundance targets while maintaining lot-to-lot reproducibility.
Previously referred to as “Recombinant polyclonal antibody,” this product is now branded as “Recombinant Superclonal™ antibody” with unchanged performance.

Target Information

IL-27 is a heterodimeric cytokine composed of EBI3 and p28 (IL-30) subunits, produced by activated antigen-presenting cells and dendritic cells. It acts on NK cells and naive CD4+ T cells and can influence mast cells and monocytes.
IL-27 signaling through WSX-1/gp130 activates JAK1, STAT1, and STAT3 pathways, promoting Th1 immune responses by inducing T-bet and suppressing GATA-3 expression.
IL-27 also exhibits antitumor activity, enhancing CTL function and inhibiting tumor growth in vivo.

For Research Use Only. Not for use in diagnostic procedures or resale without authorization.