Thermo Fisher Scientific IRF6 Monoclonal Antibody (OTI2C10), TrueMAB
IRF6 단백질을 인식하는 Mouse IgG1 단클론 항체로 Western Blot, IHC, ICC/IF, Flow Cytometry에 사용 가능. Human, Dog, Rat 반응성. Lyophilized 형태로 제공되며, PBS buffer에 8% trehalose 포함. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Dog, Human, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2C10 |
| Immunogen | Full-length human recombinant IRF6 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The IRF6 gene encodes a member of the interferon regulatory transcription factor (IRF) family. Members possess a conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain.
Mutations in IRF6 can lead to van der Woude syndrome and popliteal pterygium syndrome. This protein plays a role in palate formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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