Thermo Fisher Scientific Phospho-FANCG (Ser383) Polyclonal Antibody
FANCG 단백질의 Ser383 인산화 형태를 특이적으로 인식하는 Rabbit Polyclonal 항체. Western blot 및 파라핀 조직 IHC에 사용 가능. Human, Mouse, Rat 반응성. 1 mg/mL 액상 형태로 제공되며, -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human FANCG (Accession O15287), corresponding to amino acid residues around phosphorylated Ser383. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818077 |
Product Specific Information
This antibody detects endogenous levels of FANCG only when phosphorylated at serine 383.
Target Information
The Fanconi anemia complementation group (FANC) includes FANCA, FANCB, FANCC, FANCD1 (BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (BRIP1), FANCL, FANCM, and FANCN (PALB2).
Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair.
Members of the Fanconi anemia complementation group are related by their assembly into a common nuclear protein complex. FANCG is the protein for complementation group G.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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