Thermo Fisher Scientific GPR56 Monoclonal Antibody (3A1D7)
인간 GPR56 단백질을 인식하는 Mouse IgG1 단클론 항체로, WB, IHC, ICC/IF, Flow Cytometry, ELISA 등에 적합합니다. Protein G로 정제된 액상형이며, 4°C 또는 -20°C에서 안정적으로 보관 가능합니다. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific GPR56 Monoclonal Antibody (3A1D7)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3A1D7 |
| Immunogen | Purified recombinant fragment of human GPR56 (AA: 26–225) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3090743 |
Target Information
GPR56 is a member of the G protein-coupled receptor family containing seven transmembrane domains and a mucin-like domain in the N-terminal region. It plays a role in brain cortical patterning and binds specifically to transglutaminase 2 in the extracellular space. Expression of GPR56 is downregulated in melanoma cell lines, while overexpression can suppress tumor growth and metastasis. Mutations in this gene cause bilateral frontoparietal polymicrogyria. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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