Thermo Fisher Scientific NAPSA Monoclonal Antibody (5A6E4)
NAPSA 단백질을 인식하는 Mouse monoclonal antibody로, WB, IHC, Flow Cytometry, ELISA에 사용 가능. 인간 시료 반응성. Protein G 정제, 1 mg/mL 농도의 액상 형태. 연구용으로 폐 및 신장 관련 암 진단 연구에 활용.
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Applications and Tested Dilutions
| Application | Tested Dilution | References |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | - |
| Flow Cytometry (Flow) | 1:200–1:400 | - |
| ELISA | 1:10,000 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5A6E4 |
| Immunogen | Synthesized peptide of human NAPSA (AA: KPIFVPLSNYRDVQYc) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3090902 |
Target Information
Napsin 1 is an aspartic protease generally expressed in the lung and kidney, and in metastatic carcinomas throughout the body. It processes surfactant protein B in healthy pulmonary and renal tissues but is abnormally regulated during carcinogenesis. Napsin evaluation is useful for identifying several cancers and differentiating primary tumors from metastases. When combined with thyroid transcription factor analysis, napsin serves as a specific biomarker for carcinoma type differentiation. It is also associated with pulmonary alveolar proteinosis and protein catabolism in renal tubules.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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