Thermo Fisher Scientific AGR2 Monoclonal Antibody (OTI2B10), TrueMAB
AGR2 단백질을 표적하는 단일클론 항체로, Western blot과 IHC(P) 실험에 적합합니다. Human, Mouse, Rat 반응성. Lyophilized 형태로 제공되며, 1 mg/mL 농도. 암 연구 및 단백질 발현 분석에 활용 가능.
- 카탈로그번호
- CF809782
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2B10 |
| Immunogen | Human recombinant protein fragment (aa 21–175 of human AGR2) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
AGR2 (anterior gradient protein 2) and AGR3 are members of the anterior gradient homolog family. They are secreted cytoplasmic proteins involved in metastasis induction and p53 tumor suppressor inhibition. AGR2 may serve as a molecular marker and potential therapeutic target for hormone-responsive breast tumors.
AGR2 expression is upregulated in prostate, breast, lung, renal, and endometrial carcinomas, showing positive correlation with estrogen receptor (ER) and negative correlation with epidermal growth factor receptor (EGFR).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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