Thermo Fisher Scientific AGR2 Monoclonal Antibody (OTI5F1), TrueMAB
AGR2 단백질을 인식하는 단클론 항체로, Western blot 및 IHC(P) 실험에 적합합니다. Human, Mouse, Rat 반응성이 있으며, 정제된 IgG2b 형식의 비결합 항체입니다. 동결건조 형태로 제공되며, 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5F1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 21–175 of human AGR2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
AGR2 (anterior gradient protein 2) and AGR3 are members of the anterior gradient homolog family. These secreted cytoplasmic proteins are involved in metastasis induction and p53 tumor suppressor inhibition.
They may serve as molecular markers and potential therapeutic targets for hormone-responsive breast tumors.
AGR2 is ubiquitously expressed and upregulated in prostate, breast, lung, renal, and endometrial carcinomas.
AGR2 expression positively correlates with estrogen receptor (ER) expression and negatively with epidermal growth factor receptor (EGFR) expression.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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