Thermo Fisher Scientific CTSL1 Monoclonal Antibody (OTI1C7), TrueMAB
CTSL1 단백질을 인식하는 Mouse IgG2a 단클론 항체로 Western blot 및 IHC(P) 적용 가능. Human 반응성, 비결합형, 동결건조 형태. 고순도 친화 크로마토그래피 정제, 안정한 PBS/trehalose 버퍼 제공. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 114–333 of human CTSL produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The CTSL1 gene encodes a lysosomal cysteine proteinase crucial for intracellular protein catabolism. Its substrates include collagen, elastin, and alpha-1 protease inhibitor, which regulates neutrophil elastase activity.
This protein is associated with pathological processes such as myofibril necrosis in myopathies, myocardial ischemia, and renal tubular response to proteinuria.
It belongs to the peptidase C1 family and forms a disulfide-linked dimer composed of heavy and light chains derived from a single precursor.
At least two transcript variants encoding the same protein are known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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