
Thermo Fisher Scientific Nicotinic Acetylcholine Receptor alpha 7 (CHRNA7) (extracellular) Polyclonal Antibody, Atto 633
CHRNA7 단백질의 세포외 도메인을 인식하는 Rabbit Polyclonal Antibody로, Atto 633 형광 표지. 인간, 생쥐, 랫트 반응성. 항원 친화 크로마토그래피 정제, Flow Cytometry에 적합. 연구용으로만 사용 가능.
- 카탈로그번호
- ANC-007-FR-50UL
- 판매단위
- pk
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Thermo Fisher Scientific Nicotinic Acetylcholine Receptor alpha 7 (CHRNA7) (extracellular) Polyclonal Antibody, Atto 633
Applications
- Flow Cytometry (Flow)
Tested Dilution: 1:10
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | (C)KELVKNYNPLER, corresponding to amino acid residues 31–42 of rat nAChR alpha 7, extracellular N-terminus |
| Conjugate | Atto™ 633 |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitution: Add 50 µL double distilled water (DDW), depending on sample size.
The antibody ships as a lyophilized powder at room temperature. Upon arrival, store at -20°C.
Reconstituted solution can be stored at 4°C, protected from light, for up to 1 week.
For longer storage, aliquot and keep at -20°C. Avoid multiple freeze/thaw cycles.
Centrifuge antibody preparations before use (10,000 × g for 5 min).
Target Information
Chromosome 15 encodes over 700 genes and comprises nearly 3% of the human genome.
CHRFAM7A, a fusion protein comprised of FAM7A and AChR alpha7, is encoded by the CHRFAM7A gene, located on a region of chromosome 15 associated with neuropsychiatric disorders such as schizophrenia and bipolar affective disorder.
CHRFAM7A (also known as D-10 or CHRNA7) is a 412 amino acid multi-pass membrane protein belonging to the nicotinic acetylcholine receptor (nAChR) subfamily of ligand-gated ion channel proteins. It mediates signal transmission at synapses and is expressed in the hippocampus.
Alternative splicing of the CHRFAM7A gene produces two splice variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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