Thermo Fisher Scientific Nicotinic Acetylcholine Receptor alpha 7 (CHRNA7) (extracellular) Polyclonal Antibody, FITC

Thermo Fisher Scientific Nicotinic Acetylcholine Receptor alpha 7 (CHRNA7) (extracellular) Polyclonal Antibody, FITC

Applications

• Flow Cytometry (Flow)

Tested Dilution: 5 µg

Product Specifications

Product Specific Information

Reconstitution: Add 50 µL double distilled water (DDW), depending on sample size.
The antibody ships as a lyophilized powder at room temperature. Upon arrival, store at -20°C.
Reconstituted solution can be stored at 4°C for up to 1 week. For longer storage, aliquot and keep at -20°C.
Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10,000 × g, 5 min).

Target Information

Chromosome 15 encodes over 700 genes and comprises nearly 3% of the human genome.
CHRFAM7A, a fusion protein comprised of FAM7A and AChR alpha7, is encoded by the CHRFAM7A gene, located on a region of chromosome 15 associated with neuropsychiatric disorders such as schizophrenia and bipolar affective disorder.
CHRFAM7A (also known as D-10 or CHRNA7) is a 412 amino acid multi-pass membrane protein belonging to the nicotinic acetylcholine receptor (nAChR) subfamily of ligand-gated ion channel proteins, mediating signal transmission at synapses.
It is expressed in the hippocampus, and alternative splicing produces two splice variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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