Thermo Fisher Scientific CD160 Monoclonal Antibody (BY55), Alexa Fluor 488, eBioscience

Applications

• Flow Cytometry (Flow): 5 µL (0.25 µg)/test
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Product Specifications

Available Formats

• eFluor 660
• PE
• Request custom conjugation

Product Specific Information

This BY55 monoclonal antibody reacts with human CD160, a member of the immunoglobulin superfamily expressed on natural killer (NK) cells, natural killer T cells, activated and/or memory CD4 and CD8 T cells, gamma/delta T cells, and intraepithelial cells.
CD160 binds herpes virus entry mediator (HVEM) in a complex with LIGHT and BTLA to deliver an inhibitory signal to CD4 T cells, reducing proliferation and cytokine production.
Three alternative splice variants of CD160 have been identified in NK cells.

Applications Reported: Flow cytometric analysis
Applications Tested: Pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells.
Use at 5 µL (0.25 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL.
Cell number should be determined empirically (10⁵–10⁸ cells/test).

Excitation: 488 nm
Emission: 519 nm
Laser: Blue Laser
Filtration: 0.2 µm post-manufacturing filtered

Target Information

CD160 is a receptor with broad specificity for both classical and non-classical MHC class I molecules.
It is expressed at the cell surface as a tightly disulfide-linked multimer and is involved in cell proliferation, receptor signaling, cellular defense response, and immune regulation.

For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.

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