Thermo Fisher Scientific Phospho-Synapsin 1 (Ser9) Recombinant Rabbit Monoclonal Antibody (SN63-04)
Synapsin 1의 Ser9 인산화 형태를 인식하는 재조합 토끼 단클론 항체. Western blot 및 IHC(P) 검증 완료. 높은 특이성과 재현성을 제공하며, 동물 유래 성분이 없는 포뮬레이션. 단기 4°C, 장기 -20°C 보관.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SN63-04 |
| Immunogen | Synthetic phospho-peptide corresponding to residues surrounding Ser9 of Human Synapsin I (aa 1–50) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809563 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences are cloned from immunoreactive rabbits, and individual clones are screened to select optimal candidates for production.
Advantages include:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
SYN1 (Synapsin 1) is a member of the synapsin gene family encoding neuronal phosphoproteins associated with the cytoplasmic surface of synaptic vesicles. These proteins play key roles in synaptogenesis and modulation of neurotransmitter release, and may be implicated in neuropsychiatric diseases.
Synapsin 1 regulates axonogenesis and synaptogenesis, serving as a substrate for multiple protein kinases. Phosphorylation at Ser9 is involved in nerve terminal function. Mutations in this gene are associated with X-linked neuronal degeneration disorders such as Rett syndrome.
Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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