Thermo Fisher Scientific HRH3 Polyclonal Antibody
HRH3 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot 및 IHC(P)에서 검증됨. 인간에 반응하며, 단백질 A 정제 및 액상 형태로 제공. 신경전달물질 조절 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Histamine H3 Receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2792225 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Rhesus Monkey (100%).
- Positive Control: A431, H1299.
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
H3 Histamine Receptor regulates the release of neurotransmitters such as norepinephrine and somatostatin.
In histamine-containing neurons of the brain, the H3 receptor acts as a presynaptic autoreceptor, while in nonhistamine-containing neurons (both central and peripheral nervous systems), it acts as a presynaptic heteroreceptor.
Multiple isoforms of H3 receptors are produced by alternative splicing.
Histamine H3 receptor has been reported primarily in brain tissues. ESTs have been isolated from brain (normal and cancer), breast cancer, colon cancer, and retinoblastoma libraries.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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