Thermo Fisher Scientific BAD Polyclonal Antibody
Rabbit polyclonal antibody targeting human BAD protein for apoptosis research. Validated for Western blot applications. High purity via antigen affinity chromatography. Supplied as liquid form with glycerol for stability. Suitable for cell signaling an...
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human Bad |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.36 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792764 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Rhesus Monkey (95%), Chimpanzee (100%).
- Positive Control: 293T, A431, HeLa.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by BAD is a member of the BCL-2 family, known as regulators of programmed cell death. BAD promotes apoptosis by forming heterodimers with BCL-xL and BCL-2, reversing their death repressor activity. Its proapoptotic activity is regulated by phosphorylation through kinases such as AKT and MAPK, and phosphatase calcineurin. Alternative splicing results in two transcript variants encoding the same isoform.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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