Thermo Fisher Scientific Perilipin 1 Polyclonal Antibody
Perilipin 1 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot 및 IHC(파라핀 절편)에 적합합니다. 인간과 생쥐에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 단기 보관은 4°C, 장기 보관은 -20°C에서 권장됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:10,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human Perilipin 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.69 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792767 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (92%), Rat (92%), Pig (92%), Sheep (94%), Bovine (94%).
- Positive Control: THP-1, mouse adipose.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Adipose tissue serves as an energy reserve and is tightly regulated. Adipocytes secrete proteins such as lipoprotein lipase (LPL), leptin, Acrp30, resistin, and perilipin.
Perilipin is a lipid droplet-associated protein regulated by hormones. It localizes to the surface of lipid droplets and becomes phosphorylated by protein kinase A in response to lipolytic stimuli. Activated perilipin inhibits hormone-sensitive lipase (HSL), which hydrolyzes triacylglycerol, the main stored energy form.
Perilipin expression is restricted to adipocytes and steroidogenic cells. Two isoforms, Perilipin A and B, are produced by alternative splicing of a single gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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