Thermo Fisher Scientific SSTR3 Polyclonal Antibody
Rabbit 폴리클로날 항체로 인간 Somatostatin receptor 3(SSTR3)를 인식합니다. Western blot, IHC, ICC/IF에 사용 가능하며 고농축 액상 형태로 제공됩니다. 단기 4°C, 장기 -20°C 보관하며 U87-MG 및 뇌 조직에서 양성 대조로 활용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to human Somatostatin receptor 3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.54 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792765 |
Product Specific Information
- Keep as concentrated solution.
- Positive Control: U87-MG, U87-MG membrane extract, mouse brain, rat brain.
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
Expression of Somatostatin Receptor Type 3 (SSTR3) has been reported in brain, breast, eye, gastrointestinal tract, pancreas, and thyroid.
G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist.
All GPCRs share a structural motif consisting of seven membrane-spanning helices and exist in both active and inactive forms.
An array of activating ligands participate in the conformation of GPCRs which leads to signaling via G-proteins and downstream effectors.
Ongoing studies have shown the reactions involved in the negative regulation of GPCRs, which has significant implications for cellular physiology and pharmacological research.
Two GPCR-targeted drugs, Zyprexa (Eli Lilly) and Claritin (Schering-Plough), are examples of successful pharmaceuticals in mental health and allergy markets.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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