Thermo Fisher Scientific CD11c Monoclonal Antibody (3.9), eFluor 450, eBioscience

Applications and Tested Dilution

• Application: Flow Cytometry (Flow)
• Tested Dilution: 5 µL (0.5 µg)/test
• Publications: View 19 publications

Product Specifications

Available Formats

• Unconjugated
• Alexa Fluor 532
• Alexa Fluor 700
• APC
• APC-eFluor 780
• Biotin
• Brilliant UV 737
• Brilliant UV 805
• eFluor 506
• FITC
• PE
• PE-Cyanine5
• PE-Cyanine5.5
• PE-Cyanine7
• PE-eFluor 610
• PerCP-eFluor 710
• Super Bright 600
• Super Bright 645
• Super Bright 702
• Super Bright 780
• Request custom conjugation

Product Specific Information

Description:
The 3.9 monoclonal antibody reacts with human CD11c, a 150 kDa integrin alpha X chain. CD11c associates with beta 2 integrin to form the CD11c/CD18 heterodimer, expressed on monocytes, granulocytes, macrophages, NK cells, dendritic cells, and subsets of T and B lymphocytes. This complex binds to CD54, iC3b, and fibrinogen, playing a key role in leukocyte adhesion.

Applications Reported:
Reported for use in flow cytometric analysis.

Applications Tested:
Pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. Recommended at 5 µL (0.5 µg) per test (final volume 100 µL). Cell number can range from 10⁵ to 10⁸ cells/test.

Fluorophore Information:
eFluor® 450 is an alternative to Pacific Blue®, excited at 405 nm and emitting at 445 nm (Violet laser). Ensure instrument compatibility.
Filtration: 0.2 µm post-manufacturing filtered.

Target Information

CD11, together with CD18, forms a heterodimeric adhesion molecule.

• CD11a: Expressed in B/T lymphocytes, macrophages, monocytes, neutrophils, basophils, eosinophils.
• CD11b: Expressed by monocytes, macrophages, NK cells, some B/T cells, and granulocytes.
• CD11c: Expressed in monocytes, macrophages, NK cells, some granulocytes, and subsets of lymphocytes.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지